Rafael Giraldo Selected Research

Proteostasis Deficiencies

1/2018	Addressing Intracellular Amyloidosis in Bacteria with RepA-WH1, a Prion-Like Protein.
1/2018	Modulation of the Aggregation of the Prion-like Protein RepA-WH1 by Chaperones in a Cell-Free Expression System and in Cytomimetic Lipid Vesicles.
1/2017	Outlining Core Pathways of Amyloid Toxicity in Bacteria with the RepA-WH1 Prionoid.
3/2016	RepA-WH1, the agent of an amyloid proteinopathy in bacteria, builds oligomeric pores through lipid vesicles.
1/2016	RepA-WH1 prionoid: Clues from bacteria on factors governing phase transitions in amyloidogenesis.
10/2015	Pre-amyloid oligomers of the proteotoxic RepA-WH1 prionoid assemble at the bacterial nucleoid.
1/2015	Amyloidogenesis of bacterial prionoid RepA-WH1 recapitulates dimer to monomer transitions of RepA in DNA replication initiation.
7/2014	Aggregation interplay between variants of the RepA-WH1 prionoid in Escherichia coli.
3/2014	Direct assessment in bacteria of prionoid propagation and phenotype selection by Hsp70 chaperone.
4/2011	RepA-WH1 prionoid: a synthetic amyloid proteinopathy in a minimalist host.

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Rafael Giraldo Research Topics

Disease

12	Proteostasis Deficiencies 01/2018 - 04/2008
6	Amyloidosis 01/2018 - 09/2010
1	Neuroblastoma 01/2020
1	Stroke (Strokes) 01/2017
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2016
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 10/2015
1	Amyloid Plaque 03/2012
1	Alzheimer Disease (Alzheimer's Disease) 03/2012

Drug/Important Bio-Agent (IBA)

12	Amyloid (Amyloid Fibrils)IBA 01/2020 - 09/2010
8	Proteins (Proteins, Gene)FDA Link 01/2018 - 04/2008
4	PrionsIBA 01/2018 - 04/2011
2	DNA (Deoxyribonucleic Acid)IBA 07/2014 - 09/2010
1	EnzymesIBA 01/2017
1	Transcription Factors (Transcription Factor)IBA 01/2017
1	LigandsIBA 03/2016
1	LipidsIBA 03/2016
1	SeptinsIBA 03/2012
1	ProteomeIBA 04/2011
1	Red Fluorescent ProteinIBA 09/2010
1	A-Form DNA (A-DNA)IBA 09/2010